Usually we provide a link directly to the developer's site, to make sure you download the latest, original version of the program. Search for GCK on Bing external link. Heads up: The link above performs a search for the product installer on the Bing search engine. We do not necessarily endorse the content of the sites shown in their search results.
Use common sense before downloading software from the internet. We spend countless hours researching various file formats and software that can open, convert, create or otherwise work with those files.
If you have additional information about which types of files GCK can process, please do get in touch - we would love hearing from you.
Always run your file through a malware checker before trying to open it. Windows typically hides file extensions for known file types, which means that you shouldn't see the extension for most files.
If you're unfamiliar with the file extension, right-click on it and click on "Properties". The "General" tab will reveal the filename and the extension suffix. You can now Google it to learn more about the file type. Once you know the type of content the GCK file contains graphics, media, text , you can add the file extension to the default file associations in the computer's settings and try to open it again.
If you don't have the matching software, you will have to download it. If that still does not work, you may have to contact the developer for more guidance. For example, if you know that you have GCK files, you will be able to Google to find out which software packages use the GCK file extension. These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build.
Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above. The following sections contain reference sequences that belong to a specific genome build.
This section includes genomic Reference Sequences RefSeqs from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds contigs from both reference and alternate assemblies. Model RNAs and proteins are also reported here. The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links. National Center for Biotechnology Information , U.
Gene Genes and mapped phenotypes. Add to Clipboard. Add to Collections. File name. Summary Go to the top of the page Help. Hexokinases phosphorylate glucose to produce glucosephosphate, the first step in most glucose metabolism pathways. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucosephosphate but remains active while glucose is abundant. The use of multiple promoters and alternative splicing of this gene result in distinct protein isoforms that exhibit tissue-specific expression in the pancreas and liver.
In the pancreas, this enzyme plays a role in glucose-stimulated insulin secretion, while in the liver, this enzyme is important in glucose uptake and conversion to glycogen.
Mutations in this gene that alter enzyme activity have been associated with multiple types of diabetes and hyperinsulinemic hypoglycemia.
Genomic context Go to the top of the page Help. Annotation release Status Assembly Chr Location Genomic regions, transcripts, and products Go to the top of the page Help. Go to reference sequence details. Expression Go to the top of the page Help. See details. Bibliography Go to the top of the page Help.
Tagliaferri F, et al. Diabetes Res Clin Pract, Nov. Xu H, et al.
0コメント