Rethinking herpes simplex virus the way to oncolytic agents

Oncolytic virus therapy for cancer. Oncolytic Virotherapy. Herpes virus fusion and entry: a story with many characters. Physical state of the latent herpes simplex virus genome in a mouse model system: evidence suggesting an episomal state. Preston CM, Efstathiou S. Fatahzadeh M, Schwartz RA.

Human herpes simplex virus infections: epidemiology, pathogenesis, symptomatology, diagnosis, and management. J Am Acad Dermatol. Bloom DC. Int Rev Immunol. Gale M, Katze MG. Molecular mechanisms of interferon resistance mediated by viral-directed inhibition of PKR, the interferon-induced protein kinase.

Pharmacol Ther. Clemens MJ, Elia A. J Interferon Cytokine Res. The gamma J Biol Chem. Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Macroautophagy signaling and regulation. Curr Top Microbiol Immunol. PKR-dependent autophagic degradation of herpes simplex virus type 1.

Cell Host Microbe. Xenophagy in herpes simplex virus replication and pathogenesis. Interaction of ICP J Virol. Tumor suppressor function of the interferon-induced double-stranded RNA-activated protein kinase. Haus O. The genes of interferons and interferon-related factors: localization and relationships with chromosome aberrations in cancer. Arch Immunol Ther Exp. Induction of autophagy and inhibition of tumorigenesis by Beclin 1.

Oncolysis of pancreatic tumour cells by a gamma Gene Ther. Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by deltagamma 1 Oncogenes in Ras signalling pathway dictate host-cell permissiveness to herpes simplex virus 1. Nat Cell Biol. J Gen Virol. The herpes simplex virus virulence factor ICP J Neurovirol.

Rethinking herpes simplex virus: the way to oncolytic agents. Rev Med Virol. Oncolytic virotherapy. Nat Biotechnol. Mapping of herpes simplex virus-1 neurovirulence to gamma Replication, establishment of latency, and induced reactivation of herpes simplex virus gamma 1 J Clin Invest. Herpes simplex virus turns off the TAP to evade host immunity. EMBO J. The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex MHC -encoded peptide transporter associated with antigen processing TAP , maps to the NH2-terminal 35 residues.

J Exp Med. Mohr I, Gluzman Y. A herpesvirus genetic element which affects translation in the absence of the viral GADD34 function.

A herpes simplex virus type 1 gamma Am J Clin Oncol. Adjuvant therapy of stage III and IV malignant melanoma using granulocyte-macrophage colony-stimulating factor. J Clin Oncol. J Immunother. Steinman RM. The dendritic cell system and its role in immunogenicity. Annu Rev Immunol. Clin Cancer Res. Future Oncol. High-dose recombinant interleukin 2 therapy for patients with metastatic melanoma: analysis of patients treated between and Improved survival with ipilimumab in patients with metastatic melanoma.

N Engl J Med. Gp peptide vaccine and interleukin-2 in patients with advanced melanoma. Ann Surg Oncol. Phase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanoma.

Articles from Oncolytic Virotherapy are provided here courtesy of Dove Press. Bradley J. Blank S. Nigim F. Sugawara K. Wang J. Cancer Cell Int. Oncolytic Virotherapy for Breast Cancer Treatment. Asian Pac. Cancer Prev. Taguchi S. Thomas E. Ovarian Res. Ghouse S. Studebaker A. Chiocca E. Preclinical Toxicology of RQNestin Methods Clin. Oncolytic Herpes Simplex Virus and Immunotherapy.

BMC Immunol. Bell J. Oncolytic Virother. Ferguson M. Herrlinger U. Kanzaki A. Parker Kerrigan B. Sonabend A. Stem Cells. Kidd S. Kazimirsky G. Stem Cell Res. Herberts C. Chulpanova D. Front Pharmacol. Hakkarainen T. Ong H. Leoni V. Martuza R. Kanai R. Israyelyan A. Wang Y. Roizman B. Raman S. Andtbacka R. Grigg C. Puzanov I. Hua L. Expert Opin. Chesney J. Harrington K. Clin Cancer Res. Sze D. Koch M. Thomas S. Haines B. Cancer Immunol. Lambright E.

Delman K. Ikeda K. Varghese S. Lou E. Acta Oncol. Eissa I. Viruses for Tumor Therapy. Cell Host Microbe. Support Center Support Center. External link. Please review our privacy policy. Glioblasoma [ 42 ] Colon carcinoma [ 43 ] Sarcoma [ 44 ]. Nestin promoter drives the expression of ICP Glioma [ 45 ]. Glioma [ 46 , 47 ] Cervical cancer [ 48 ].

Meningioma [ 49 ] Gastic cancer [ 50 ] Liver cancer [ 51 ] Breast cancer [ 52 ] Thyroid carcinoma [ 53 ] Urological cancers [ 54 ]. Glioblastoma [ 41 ]. G expressing IL Ovarian cancer [ 55 ] Breast cancer [ 56 ]. Advanced melanoma [ 18 ]. Completed [ 89 ]. Head and neck cancer. Active, not recruiting [ 90 ]. Completed [ 87 ]. Active, not recruiting.

Enrolling by invitation. Any tumor type. Resection surgery. No longer available. Chemotherapy or PV Soft tissue sarcoma. Completed [ 91 ]. Squamous cell carcinoma of the head and neck. Liver cancer. Breast cancer. Advanced non-CNS tumors. Melanoma, Markel cell carcinoma, and other tumors. Melanoma, lymphoma, lung cancer, and other. Triple negative breast cancer. Melanoma and herpetic infection. Solid tumors and mycosis fungoides.

Pancreatic cancer. Metastatic colorectal and breast cancers. Rectal cancer. Non-melanoma skin cancer. Sarcoma and melanoma.

Stage IV peritoneal malignancy. Active, not Recruiting. Lung cancer. Bladder carcinoma. Squamous cell carcinoma. Chemotherapy or endocrine therapy. Skin angiosarcoma. Squamous cell carcinoma of the skin.

Not yet recruiting. Kaposi sarcoma. Squamous cell carcinoma of the skin, breast carcinoma, melanoma, head and neck cancer. Solid tumors. Clin Cancer Res, 1 Pt 1 Cancer Res, 19 Gene Ther, 4 Hum Gene Ther, 10 Clin Cancer Res, 22 Cancer Res, 17 Viruses , 13 9 , 01 Sep Viruses , 13 10 , 16 Oct Viruses , 13 9 , 24 Aug Future Microbiol , , 23 Mar Cited by: 0 articles PMID: RNA Biol , 18 5 , 22 Mar To arrive at the top five similar articles we use a word-weighted algorithm to compare words from the Title and Abstract of each citation.

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